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Three dimensional structure directs T-cell epitope dominance associated with allergy
BACKGROUND: CD4+ T-cell epitope immunodominance is not adequately explained by peptide selectivity in class II major histocompatibility proteins, but it has been correlated with adjacent segments of conformational flexibility in several antigens. METHODS: The published T-cell responses to two venom...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553403/ https://www.ncbi.nlm.nih.gov/pubmed/18793409 http://dx.doi.org/10.1186/1476-7961-6-9 |