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Elimination of Schistosoma mansoni Adult Worms by Rhesus Macaques: Basis for a Therapeutic Vaccine?

BACKGROUND: Among animal models of schistosomiasis, the rhesus macaque is unique in that an infection establishes but egg excretion rapidly diminishes, potentially due to loss of adult worms from the portal system via shunts or death by immune attack. PRINCIPAL FINDINGS: To investigate this, six rhe...

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Detalles Bibliográficos
Autores principales: Wilson, R. Alan, Langermans, Jan A. M., van Dam, Govert J., Vervenne, Richard A., Hall, Stephanie L., Borges, William C., Dillon, Gary P., Thomas, Alan W., Coulson, Patricia S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553480/
https://www.ncbi.nlm.nih.gov/pubmed/18820739
http://dx.doi.org/10.1371/journal.pntd.0000290