Cell type differences in activity of the Streptomyces bacteriophage ϕC31 integrase

Genomic integration by the Streptomyces bacteriophage ϕC31 integrase is a promising tool for non-viral gene therapy of various genetic disorders. We investigated the ϕC31 integrase recombination activity in T cell derived cell lines, primary T lymphocytes and CD34(+) haematopoietic stem cells in com...

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Detalles Bibliográficos
Autores principales: Maucksch, Christof, Aneja, Manish Kumar, Hennen, Elisabeth, Bohla, Alexander, Hoffmann, Florian, Elfinger, Markus, Rosenecker, Joseph, Rudolph, Carsten
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553569/
https://www.ncbi.nlm.nih.gov/pubmed/18718925
http://dx.doi.org/10.1093/nar/gkn532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553569/
https://www.ncbi.nlm.nih.gov/pubmed/18718925
http://dx.doi.org/10.1093/nar/gkn532

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