Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA

Here, we report the first example that one enantiomer of a supramolecular cylinder can selectively stabilize human telomeric G-quadruplex DNA. The P-enantiomer of this cylinder has a strong preference for G-quadruplex over duplex DNA and, in the presence of sodium, can convert G-quadruplexes from an...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Haijia, Wang, Xiaohui, Fu, Manliang, Ren, Jinsong, Qu, Xiaogang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Chemistry and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553577/
https://www.ncbi.nlm.nih.gov/pubmed/18776218
http://dx.doi.org/10.1093/nar/gkn569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553577/
https://www.ncbi.nlm.nih.gov/pubmed/18776218
http://dx.doi.org/10.1093/nar/gkn569

Ejemplares similares