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Mix and measure fluorescence screening for selective quadruplex binders

The human genome contains thousands of regions, including that of the telomere, that have the potential to form quadruplex structures. Many of these regions are potential targets for therapeutic intervention. There are many different folding patterns for quadruplex DNAs and the loops exhibit much mo...

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Detalles Bibliográficos
Autores principales: Paramasivan, Sattanathan, Bolton, Philip H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553591/
https://www.ncbi.nlm.nih.gov/pubmed/18663011
http://dx.doi.org/10.1093/nar/gkn487