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Mix and measure fluorescence screening for selective quadruplex binders
The human genome contains thousands of regions, including that of the telomere, that have the potential to form quadruplex structures. Many of these regions are potential targets for therapeutic intervention. There are many different folding patterns for quadruplex DNAs and the loops exhibit much mo...
Autores principales: | Paramasivan, Sattanathan, Bolton, Philip H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553591/ https://www.ncbi.nlm.nih.gov/pubmed/18663011 http://dx.doi.org/10.1093/nar/gkn487 |
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