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Activated transcription via mammalian amino acid response elements does not require enhanced recruitment of the Mediator complex
It is unclear whether Mediator complex in yeast is necessary for all RNA polymerase II (Pol II) transcription or if it is limited to genes activated by environmental stress. In mammals, amino acid limitation induces SNAT2 transcription through ATF4 binding at an amino acid response element. ATF4 is...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553592/ https://www.ncbi.nlm.nih.gov/pubmed/18757893 http://dx.doi.org/10.1093/nar/gkn538 |