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Use of the viral 2A peptide for bicistronic expression in transgenic mice

BACKGROUND: Transgenic animals are widely used in biomedical research and biotechnology. Multicistronic constructs, in which several proteins are encoded by a single messenger RNA, are commonly used in genetically engineered animals. This is currently done by using an internal ribosomal entry site t...

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Detalles Bibliográficos
Autores principales: Trichas, Georgios, Begbie, Jo, Srinivas, Shankar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553761/
https://www.ncbi.nlm.nih.gov/pubmed/18793381
http://dx.doi.org/10.1186/1741-7007-6-40