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Use of the viral 2A peptide for bicistronic expression in transgenic mice
BACKGROUND: Transgenic animals are widely used in biomedical research and biotechnology. Multicistronic constructs, in which several proteins are encoded by a single messenger RNA, are commonly used in genetically engineered animals. This is currently done by using an internal ribosomal entry site t...
Autores principales: | Trichas, Georgios, Begbie, Jo, Srinivas, Shankar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553761/ https://www.ncbi.nlm.nih.gov/pubmed/18793381 http://dx.doi.org/10.1186/1741-7007-6-40 |
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