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A robust linear regression based algorithm for automated evaluation of peptide identifications from shotgun proteomics by use of reversed-phase liquid chromatography retention time

BACKGROUND: Rejection of false positive peptide matches in database searches of shotgun proteomic experimental data is highly desirable. Several methods have been developed to use the peptide retention time as to refine and improve peptide identifications from database search algorithms. This report...

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Detalles Bibliográficos
Autores principales: Xu, Hua, Yang, Lanhao, Freitas, Michael A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553802/
https://www.ncbi.nlm.nih.gov/pubmed/18713471
http://dx.doi.org/10.1186/1471-2105-9-347