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Interconvertible Lac Repressor–DNA Loops Revealed by Single-Molecule Experiments
At many promoters, transcription is regulated by simultaneous binding of a protein to multiple sites on DNA, but the structures and dynamics of such transcription factor-mediated DNA loops are poorly understood. We directly examined in vitro loop formation mediated by Escherichia coli lactose repres...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553838/ https://www.ncbi.nlm.nih.gov/pubmed/18828671 http://dx.doi.org/10.1371/journal.pbio.0060232 |