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Caenorhabditis elegans HCF-1 Functions in Longevity Maintenance as a DAF-16 Regulator

The transcription factor DAF-16/forkhead box O (FOXO) is a critical longevity determinant in diverse organisms, however the molecular basis of how its transcriptional activity is regulated remains largely unknown. We report that the Caenorhabditis elegans homolog of host cell factor 1 (HCF-1) repres...

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Detalles Bibliográficos
Autores principales: Li, Ji, Ebata, Atsushi, Dong, Yuqing, Rizki, Gizem, Iwata, Terri, Lee, Siu Sylvia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553839/
https://www.ncbi.nlm.nih.gov/pubmed/18828672
http://dx.doi.org/10.1371/journal.pbio.0060233