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Caenorhabditis elegans HCF-1 Functions in Longevity Maintenance as a DAF-16 Regulator
The transcription factor DAF-16/forkhead box O (FOXO) is a critical longevity determinant in diverse organisms, however the molecular basis of how its transcriptional activity is regulated remains largely unknown. We report that the Caenorhabditis elegans homolog of host cell factor 1 (HCF-1) repres...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2553839/ https://www.ncbi.nlm.nih.gov/pubmed/18828672 http://dx.doi.org/10.1371/journal.pbio.0060233 |