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High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

Recent studies of the HapMap lymphoblastoid cell lines have identified large numbers of quantitative trait loci for gene expression (eQTLs). Reanalyzing these data using a novel Bayesian hierarchical model, we were able to create a surprisingly high-resolution map of the typical locations of sites t...

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Detalles Bibliográficos
Autores principales: Veyrieras, Jean-Baptiste, Kudaravalli, Sridhar, Kim, Su Yeon, Dermitzakis, Emmanouil T., Gilad, Yoav, Stephens, Matthew, Pritchard, Jonathan K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556086/
https://www.ncbi.nlm.nih.gov/pubmed/18846210
http://dx.doi.org/10.1371/journal.pgen.1000214