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IKKα, a critical regulator of epidermal differentiation and a suppressor of skin cancer
IκB kinase α (IKKα), one of the two catalytic subunits of the IKK complex involved in nuclear factor κB (NF-κB) activation, also functions as a molecular switch that controls epidermal differentiation. This unexpected function requires IKKα nuclear translocation but does not depend on its kinase act...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556095/ https://www.ncbi.nlm.nih.gov/pubmed/18818691 http://dx.doi.org/10.1038/emboj.2008.196 |