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Prevalence of variations in melanoma susceptibility genes among Slovenian melanoma families

BACKGROUND: Two high-risk genes have been implicated in the development of CM (cutaneous melanoma). Germline mutations of the CDKN2A gene are found in < 25% of melanoma-prone families and there are only seven families with mutation of the CDK4 gene reported to date. Beside those high penetrance g...

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Detalles Bibliográficos
Autores principales: Peric, Barbara, Cerkovnik, Petra, Novakovic, Srdjan, Zgajnar, Janez, Besic, Nikola, Hocevar, Marko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556318/
https://www.ncbi.nlm.nih.gov/pubmed/18803811
http://dx.doi.org/10.1186/1471-2350-9-86