Cargando…

Meiotic Regulation of TPX2 Protein Levels Governs Cell Cycle Progression in Mouse Oocytes

Formation of female gametes requires acentriolar spindle assembly during meiosis. Mitotic spindles organize from centrosomes and via local activation of the RanGTPase on chromosomes. Vertebrate oocytes present a RanGTP gradient centred on chromatin at all stages of meiotic maturation. However, this...

Descripción completa

Detalles Bibliográficos
Autores principales: Brunet, Stéphane, Dumont, Julien, Lee, Karen W., Kinoshita, Kazuhisa, Hikal, Pascale, Gruss, Oliver J., Maro, Bernard, Verlhac, Marie-Hélène
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556383/
https://www.ncbi.nlm.nih.gov/pubmed/18833336
http://dx.doi.org/10.1371/journal.pone.0003338