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Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

BACKGROUND: Alzheimer's disease (AD) is characterized by extensive loss of neurons in the brain of AD patients. Intracellular accumulation of beta-amyloid peptide (Aβ) has also shown to occur in AD. Neuro-inflammation has been known to play a role in the pathogenesis of AD. METHODS: In this stu...

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Detalles Bibliográficos
Autores principales: Lee, Jae Woong, Lee, Yong Kyung, Yuk, Dong Yeon, Choi, Dong Young, Ban, Sang Bae, Oh, Ki Wan, Hong, Jin Tae
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556656/
https://www.ncbi.nlm.nih.gov/pubmed/18759972
http://dx.doi.org/10.1186/1742-2094-5-37