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Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells

BACKGROUND: The transmissible spongiform encephalopathies, otherwise known as prion diseases, occur following the conversion of the cellular prion protein (PrP(C)) to an alternatively folded, disease-associated isoform (PrP(Sc)). Recent studies suggest that this conversion occurs via a cholesterol-s...

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Detalles Bibliográficos
Autores principales: Bate, Clive, Tayebi, Mourad, Diomede, Luisa, Salmona, Mario, Williams, Alun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556658/
https://www.ncbi.nlm.nih.gov/pubmed/18789130
http://dx.doi.org/10.1186/1741-7007-6-39