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Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cells
BACKGROUND: The transmissible spongiform encephalopathies, otherwise known as prion diseases, occur following the conversion of the cellular prion protein (PrP(C)) to an alternatively folded, disease-associated isoform (PrP(Sc)). Recent studies suggest that this conversion occurs via a cholesterol-s...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556658/ https://www.ncbi.nlm.nih.gov/pubmed/18789130 http://dx.doi.org/10.1186/1741-7007-6-39 |