Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation

We recently demonstrated the pivotal role of the transcription factor (TF) activating TF 3 (ATF3) in dampening inflammation. We demonstrate that ATF3 also ameliorates allergen-induced airway inflammation and hyperresponsiveness in a mouse model of human asthma. ATF3 expression was increased in the l...

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Detalles Bibliográficos
Autores principales: Gilchrist, Mark, Henderson, William R., Clark, April E., Simmons, Randi M., Ye, Xin, Smith, Kelly D., Aderem, Alan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556774/
https://www.ncbi.nlm.nih.gov/pubmed/18794337
http://dx.doi.org/10.1084/jem.20072254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556774/
https://www.ncbi.nlm.nih.gov/pubmed/18794337
http://dx.doi.org/10.1084/jem.20072254

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