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Activating transcription factor 3 is a negative regulator of allergic pulmonary inflammation
We recently demonstrated the pivotal role of the transcription factor (TF) activating TF 3 (ATF3) in dampening inflammation. We demonstrate that ATF3 also ameliorates allergen-induced airway inflammation and hyperresponsiveness in a mouse model of human asthma. ATF3 expression was increased in the l...
Autores principales: | Gilchrist, Mark, Henderson, William R., Clark, April E., Simmons, Randi M., Ye, Xin, Smith, Kelly D., Aderem, Alan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556774/ https://www.ncbi.nlm.nih.gov/pubmed/18794337 http://dx.doi.org/10.1084/jem.20072254 |
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