Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease

Maintaining tolerance of T cells to self-antigens is essential to avoid autoimmune disease. How self-reactive T cells are kept functionally inactive is, however, unknown. In this study, we show that early growth response gene 2 (Egr-2), a zinc-finger transcription factor, is expressed in CD44(high)...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Bo, Symonds, Alistair L.J., Martin, Joanne E., Kioussis, Dimitris, Wraith, David C., Li, Suling, Wang, Ping
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556781/
https://www.ncbi.nlm.nih.gov/pubmed/18779345
http://dx.doi.org/10.1084/jem.20080187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556781/
https://www.ncbi.nlm.nih.gov/pubmed/18779345
http://dx.doi.org/10.1084/jem.20080187

Ejemplares similares