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Ly6c(+) “inflammatory monocytes” are microglial precursors recruited in a pathogenic manner in West Nile virus encephalitis
In a lethal West Nile virus (WNV) model, central nervous system infection triggered a threefold increase in CD45(int)/CD11b(+)/CD11c(−) microglia at days 6–7 postinfection (p.i.). Few microglia were proliferating, suggesting that the increased numbers were derived from a migratory precursor cell. De...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556789/ https://www.ncbi.nlm.nih.gov/pubmed/18779347 http://dx.doi.org/10.1084/jem.20080421 |