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Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

Accumulation of myeloid-derived suppressor cells (MDSCs) associated with inhibition of dendritic cell (DC) differentiation is one of the major immunological abnormalities in cancer and leads to suppression of antitumor immune responses. The molecular mechanism of this phenomenon remains unclear. We...

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Detalles Bibliográficos
Autores principales: Cheng, Pingyan, Corzo, Cesar A., Luetteke, Noreen, Yu, Bin, Nagaraj, Srinivas, Bui, Marylin M., Ortiz, Myrna, Nacken, Wolfgang, Sorg, Clemens, Vogl, Thomas, Roth, Johannes, Gabrilovich, Dmitry I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556797/
https://www.ncbi.nlm.nih.gov/pubmed/18809714
http://dx.doi.org/10.1084/jem.20080132