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Mouse T-cells restrict replication of human immunodeficiency virus at the level of integration

BACKGROUND: The development of an immunocompetent, genetically modified mouse model to study HIV-1 pathogenesis and to test antiviral strategies has been hampered by the fact that cells from native mice do not or only inefficiently support several steps of the HIV-1 replication cycle. Upon HIV-1 inf...

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Detalles Bibliográficos
Autores principales: Tervo, Hanna-Mari, Goffinet, Christine, Keppler, Oliver T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557013/
https://www.ncbi.nlm.nih.gov/pubmed/18611257
http://dx.doi.org/10.1186/1742-4690-5-58