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The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes

The accuracy of chromosome segregation is enhanced by the spindle assembly checkpoint (SAC). The SAC is thought to monitor two distinct events: attachment of kinetochores to microtubules and the stretch of the centromere between the sister kinetochores that arises only when the chromosome becomes pr...

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Detalles Bibliográficos
Autores principales: O'Connell, Christopher B., Lončarek, Jadranka, Hergert, Polla, Kourtidis, Antonis, Conklin, Douglas S., Khodjakov, Alexey
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557037/
https://www.ncbi.nlm.nih.gov/pubmed/18824563
http://dx.doi.org/10.1083/jcb.200801038