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The spindle assembly checkpoint is satisfied in the absence of interkinetochore tension during mitosis with unreplicated genomes
The accuracy of chromosome segregation is enhanced by the spindle assembly checkpoint (SAC). The SAC is thought to monitor two distinct events: attachment of kinetochores to microtubules and the stretch of the centromere between the sister kinetochores that arises only when the chromosome becomes pr...
Autores principales: | O'Connell, Christopher B., Lončarek, Jadranka, Hergert, Polla, Kourtidis, Antonis, Conklin, Douglas S., Khodjakov, Alexey |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557037/ https://www.ncbi.nlm.nih.gov/pubmed/18824563 http://dx.doi.org/10.1083/jcb.200801038 |
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