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AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis

The mechanisms by which mammalian epidermal stem cells cease to proliferate and embark upon terminal differentiation are still poorly understood. By conditionally ablating two highly expressed transcription factors, AP-2α and AP-2γ, we unmasked functional redundancies and discovered an essential rol...

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Detalles Bibliográficos
Autores principales: Wang, Xuan, Pasolli, H. Amalia, Williams, Trevor, Fuchs, Elaine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557040/
https://www.ncbi.nlm.nih.gov/pubmed/18824566
http://dx.doi.org/10.1083/jcb.200804030