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AP-2 factors act in concert with Notch to orchestrate terminal differentiation in skin epidermis
The mechanisms by which mammalian epidermal stem cells cease to proliferate and embark upon terminal differentiation are still poorly understood. By conditionally ablating two highly expressed transcription factors, AP-2α and AP-2γ, we unmasked functional redundancies and discovered an essential rol...
Autores principales: | Wang, Xuan, Pasolli, H. Amalia, Williams, Trevor, Fuchs, Elaine |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557040/ https://www.ncbi.nlm.nih.gov/pubmed/18824566 http://dx.doi.org/10.1083/jcb.200804030 |
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