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Grapes(Chk1) prevents nuclear CDK1 activation by delaying cyclin B nuclear accumulation

Entry into mitosis is characterized by a dramatic remodeling of nuclear and cytoplasmic compartments. These changes are driven by cyclin-dependent kinase 1 (CDK1) activity, yet how cytoplasmic and nuclear CDK1 activities are coordinated is unclear. We injected cyclin B (CycB) into Drosophila melanog...

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Detalles Bibliográficos
Autores principales: Royou, Anne, McCusker, Derek, Kellogg, Douglas R., Sullivan, William
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557043/
https://www.ncbi.nlm.nih.gov/pubmed/18824564
http://dx.doi.org/10.1083/jcb.200801153