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Grapes(Chk1) prevents nuclear CDK1 activation by delaying cyclin B nuclear accumulation
Entry into mitosis is characterized by a dramatic remodeling of nuclear and cytoplasmic compartments. These changes are driven by cyclin-dependent kinase 1 (CDK1) activity, yet how cytoplasmic and nuclear CDK1 activities are coordinated is unclear. We injected cyclin B (CycB) into Drosophila melanog...
Autores principales: | Royou, Anne, McCusker, Derek, Kellogg, Douglas R., Sullivan, William |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557043/ https://www.ncbi.nlm.nih.gov/pubmed/18824564 http://dx.doi.org/10.1083/jcb.200801153 |
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