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Autonomy and robustness of translocation through the nuclear pore complex: a single-molecule study

All molecular traffic between nucleus and cytoplasm occurs via the nuclear pore complex (NPC) within the nuclear envelope. In this study we analyzed the interactions of the nuclear transport receptors kapα2, kapβ1, kapβ1ΔN44, and kapβ2, and the model transport substrate, BSA-NLS, with NPCs to determ...

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Detalles Bibliográficos
Autores principales: Dange, Thomas, Grünwald, David, Grünwald, Antje, Peters, Reiner, Kubitscheck, Ulrich
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557044/
https://www.ncbi.nlm.nih.gov/pubmed/18824568
http://dx.doi.org/10.1083/jcb.200806173