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Beneficial Effects of HIV Peptidase Inhibitors on Fonsecaea pedrosoi: Promising Compounds to Arrest Key Fungal Biological Processes and Virulence

BACKGROUND: Fonsecaea pedrosoi is the principal etiologic agent of chromoblastomycosis, a fungal disease whose pathogenic events are poorly understood. Current therapy for chromoblastomycosis is suboptimal due to toxicity of the available therapeutic agents and the emergence of drug resistance. Comp...

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Detalles Bibliográficos
Autores principales: Palmeira, Vanila F., Kneipp, Lucimar F., Rozental, Sonia, Alviano, Celuta S., Santos, André L. S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2557140/
https://www.ncbi.nlm.nih.gov/pubmed/18852883
http://dx.doi.org/10.1371/journal.pone.0003382