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Circulating C3 is necessary and sufficient for induction of autoantibody-mediated arthritis in a mouse model
OBJECTIVE: For the inflammation characteristic of rheumatoid arthritis, the relative contribution of mediators produced locally in the synovium versus those circulating systemically is unknown. Complement factor C3 is made in rheumatoid synovium and has been proposed to be a crucial driver of inflam...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559465/ https://www.ncbi.nlm.nih.gov/pubmed/17763447 http://dx.doi.org/10.1002/art.22859 |