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HIV-2 neutralization by intact V3-specific Fab fragments

The V3 region of both HIV-1 gp120 and HIV-2 gp125 surface glycoprotein has been described as a target for neutralizing antibodies. In this study a conformation-sensitive (3C4) and a linear site-specific (7C8) anti-HIV-2 V3 monoclonal antibody (mAb) were characterized. The neutralization capacity of...

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Detalles Bibliográficos
Autores principales: Sourial, Samer, Nilsson, Charlotta
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559833/
https://www.ncbi.nlm.nih.gov/pubmed/18706111
http://dx.doi.org/10.1186/1743-422X-5-96