Passive administration of monoclonal antibodies to Anthrolysin O prolong survival in mice lethally infected with Bacillus anthracis

BACKGROUND: Bacillus anthracis has two major virulence factors: a tripartite toxin that produces lethal and edema toxins and a polyglutamic acid capsule. A recent report suggested that a toxin belonging to the cholesterol dependant cytolysin (CDC) family, anthrolysin O (ALO) was a new virulence fact...

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Detalles Bibliográficos
Autores principales: Nakouzi, Antonio, Rivera, Johanna, Rest, Richard F, Casadevall, Arturo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559844/
https://www.ncbi.nlm.nih.gov/pubmed/18811967
http://dx.doi.org/10.1186/1471-2180-8-159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559844/
https://www.ncbi.nlm.nih.gov/pubmed/18811967
http://dx.doi.org/10.1186/1471-2180-8-159

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