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A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology
We present a mixture model-based analysis for identifying differences in the distribution of RNA polymerase II (Pol II) in transcribed regions, measured using ChIP-seq (chromatin immunoprecipitation following massively parallel sequencing technology). The statistical model assumes that the number of...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559888/ https://www.ncbi.nlm.nih.gov/pubmed/18831789 http://dx.doi.org/10.1186/1471-2164-9-S2-S23 |