A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology

We present a mixture model-based analysis for identifying differences in the distribution of RNA polymerase II (Pol II) in transcribed regions, measured using ChIP-seq (chromatin immunoprecipitation following massively parallel sequencing technology). The statistical model assumes that the number of...

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Detalles Bibliográficos
Autores principales: Feng, Weixing, Liu, Yunlong, Wu, Jiejun, Nephew, Kenneth P, Huang, Tim HM, Li, Lang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2559888/
https://www.ncbi.nlm.nih.gov/pubmed/18831789
http://dx.doi.org/10.1186/1471-2164-9-S2-S23

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