Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection

BACKGROUND: A subset of the virus-specific CD8+ cytotoxic T lymphocytes (CTL) isolated from the lungs of mice infected with human respiratory syncytial virus (RSV) is impaired in the ability to secrete interferon γ (IFNγ), a measure of functionality. It was suggested that the impairment specifically...

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Detalles Bibliográficos
Autores principales: DiNapoli, Joshua M, Murphy, Brian R, Collins, Peter L, Bukreyev, Alexander
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561024/
https://www.ncbi.nlm.nih.gov/pubmed/18816384
http://dx.doi.org/10.1186/1743-422X-5-105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561024/
https://www.ncbi.nlm.nih.gov/pubmed/18816384
http://dx.doi.org/10.1186/1743-422X-5-105

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