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Impairment of the CD8+ T cell response in lungs following infection with human respiratory syncytial virus is specific to the anatomical site rather than the virus, antigen, or route of infection
BACKGROUND: A subset of the virus-specific CD8+ cytotoxic T lymphocytes (CTL) isolated from the lungs of mice infected with human respiratory syncytial virus (RSV) is impaired in the ability to secrete interferon γ (IFNγ), a measure of functionality. It was suggested that the impairment specifically...
Autores principales: | DiNapoli, Joshua M, Murphy, Brian R, Collins, Peter L, Bukreyev, Alexander |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561024/ https://www.ncbi.nlm.nih.gov/pubmed/18816384 http://dx.doi.org/10.1186/1743-422X-5-105 |
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