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"TOF2H": A precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI approach, covering the data pipeline from spectral acquisition to HDX rate analysis

BACKGROUND: Protein-amide proton hydrogen-deuterium exchange (HDX) is used to investigate protein conformation, conformational changes and surface binding sites for other molecules. To our knowledge, software tools to automate data processing and analysis from sample fractionating (LC-MALDI) mass-sp...

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Detalles Bibliográficos
Autores principales: Nikamanon, Pornpat, Pun, Elroy, Chou, Wayne, Koter, Marek D, Gershon, Paul D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2561049/
https://www.ncbi.nlm.nih.gov/pubmed/18803853
http://dx.doi.org/10.1186/1471-2105-9-387