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Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores

Summary: In genetics, many evolutionary pathways can be modeled by the ordered accumulation of permanent changes. Mixture models of mutagenetic trees have been used to describe disease progression in cancer and in HIV. In cancer, progression is modeled by the accumulation of chromosomal gains and lo...

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Detalles Bibliográficos
Autores principales: Bogojeska, Jasmina, Alexa, Adrian, Altmann, André, Lengauer, Thomas, Rahnenführer, Jörg
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562010/
https://www.ncbi.nlm.nih.gov/pubmed/18718947
http://dx.doi.org/10.1093/bioinformatics/btn410