Anti proliferative activity of ELACYT™ (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells

This study evaluated combination drug partners for CP-4055, the C18:1(Δ9,trans) unsaturated fatty acid ester of cytarabine in HL-60 and U937 cells. Growth inhibition was assessed by ATP assay and drug interaction by the combination index and three dimensional methods. Synergy was observed in HL-60 c...

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Detalles Bibliográficos
Autores principales: Adams, David J., Sandvold, Marit L., Myhren, Finn, Jacobsen, Tove F., Giles, Frank, Rizzieri, David A.
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562023/
https://www.ncbi.nlm.nih.gov/pubmed/18398748
http://dx.doi.org/10.1080/10428190801935752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562023/
https://www.ncbi.nlm.nih.gov/pubmed/18398748
http://dx.doi.org/10.1080/10428190801935752

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