Identification of Pore Residues Engaged in Determining Divalent Cationic Permeation in Transient Receptor Potential Melastatin Subtype Channel 2

The molecular basis for divalent cationic permeability in transient receptor potential melastatin subtype (TRPM) channels is not fully understood. Here we studied the roles of all eight acidic residues, glutamate or aspartate, and also the glutamine residue between pore helix and selectivity filter...

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Detalles Bibliográficos
Autores principales: Xia, Rong, Mei, Zhu-Zhong, Mao, Hong-Ju, Yang, Wei, Dong, Li, Bradley, Helen, Beech, David J., Jiang, Lin-Hua
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562080/
https://www.ncbi.nlm.nih.gov/pubmed/18687688
http://dx.doi.org/10.1074/jbc.M801049200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562080/
https://www.ncbi.nlm.nih.gov/pubmed/18687688
http://dx.doi.org/10.1074/jbc.M801049200

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