Cargando…

Identification of Pore Residues Engaged in Determining Divalent Cationic Permeation in Transient Receptor Potential Melastatin Subtype Channel 2

The molecular basis for divalent cationic permeability in transient receptor potential melastatin subtype (TRPM) channels is not fully understood. Here we studied the roles of all eight acidic residues, glutamate or aspartate, and also the glutamine residue between pore helix and selectivity filter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Rong, Mei, Zhu-Zhong, Mao, Hong-Ju, Yang, Wei, Dong, Li, Bradley, Helen, Beech, David J., Jiang, Lin-Hua
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562080/ https://www.ncbi.nlm.nih.gov/pubmed/18687688 http://dx.doi.org/10.1074/jbc.M801049200

Ejemplares similares

Permeation Properties of a P2X Receptor in the Green Algae Ostreococcus tauri
por: Fountain, Samuel J., et al.
Publicado: (2008)

High Yield Heterologous Expression of Wild-type and Mutant Cu(+)-ATPase (ATP7B, Wilson Disease Protein) for Functional Characterization of Catalytic Activity and Serine Residues Undergoing Copper-dependent Phosphorylation
por: Pilankatta, Rajendra, et al.
Publicado: (2009)

Subunit Organization in the TatA Complex of the Twin Arginine Protein Translocase: A SITE-DIRECTED EPR SPIN LABELING STUDY
por: White, Gaye F., et al.
Publicado: (2010)

Steroidogenic Activity of StAR Requires Contact with Mitochondrial VDAC1 and Phosphate Carrier Protein
por: Bose, Mahuya, et al.
Publicado: (2008)

Time-resolved Mechanism of Extracellular Gate Opening and Substrate Binding in a Glutamate Transporter
por: Shrivastava, Indira H., et al.
Publicado: (2008)

The Reticulon and Dp1/Yop1p Proteins Form Immobile Oligomers in the Tubular Endoplasmic Reticulum
por: Shibata, Yoko, et al.
Publicado: (2008)

An Unconventional Diacylglycerol Kinase That Regulates Phospholipid Synthesis and Nuclear Membrane Growth
por: Han, Gil-Soo, et al.
Publicado: (2008)

Structural Determinants of Ca(2+) Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor
por: Livesey, Matthew R., et al.
Publicado: (2008)

Analysis of Polypeptide Movement in the SecY Channel during SecA-mediated Protein Translocation
por: Erlandson, Karl J., et al.
Publicado: (2008)

Intermediate Phosphorylation Reactions in the Mechanism of ATP Utilization by the Copper ATPase (CopA) of Thermotoga maritima
por: Hatori, Yuta, et al.
Publicado: (2008)

Rab3GEP Is the Non-redundant Guanine Nucleotide Exchange Factor for Rab27a in Melanocytes
por: Figueiredo, Ana C., et al.
Publicado: (2008)

Molecular Shape, Architecture, and Size of P2X(4) Receptors Determined Using Fluorescence Resonance Energy Transfer and Electron Microscopy
por: Young, Mark T., et al.
Publicado: (2008)

Crystal Structure of Soluble Domain of Malaria Sporozoite Protein UIS3 in Complex with Lipid
por: Sharma, Ashwani, et al.
Publicado: (2008)

AcrAB Multidrug Efflux Pump Regulation in Salmonella enterica serovar Typhimurium by RamA in Response to Environmental Signals
por: Nikaido, Eiji, et al.
Publicado: (2008)

Analysis of the Synaptotagmin Family during Reconstituted Membrane Fusion: UNCOVERING A CLASS OF INHIBITORY ISOFORMS
por: Bhalla, Akhil, et al.
Publicado: (2008)

Nonmitochondrial ATP/ADP Transporters Accept Phosphate as Third Substrate
por: Trentmann, Oliver, et al.
Publicado: (2008)

MacB ABC Transporter Is a Dimer Whose ATPase Activity and Macrolide-binding Capacity Are Regulated by the Membrane Fusion Protein MacA
por: Lin, Hong Ting, et al.
Publicado: (2009)

Cell Entry of Arginine-rich Peptides Is Independent of Endocytosis
por: Ter-Avetisyan, Gohar, et al.
Publicado: (2009)

Mechanistic Insight into Control of CFTR by AMPK
por: Kongsuphol, Patthara, et al.
Publicado: (2009)

The N-terminal Amphipathic α-Helix of Viperin Mediates Localization to the Cytosolic Face of the Endoplasmic Reticulum and Inhibits Protein Secretion
por: Hinson, Ella R., et al.
Publicado: (2009)

Interaction of the Aromatics Tyr-72/Trp-288 in the Interface of the Extracellular and Transmembrane Domains Is Essential for Proton Gating of Acid-sensing Ion Channels
por: Li, Tianbo, et al.
Publicado: (2009)

The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction
por: Schnizler, Mikael K., et al.
Publicado: (2009)

PICK1-mediated Glutamate Receptor Subunit 2 (GluR2) Trafficking Contributes to Cell Death in Oxygen/Glucose-deprived Hippocampal Neurons
por: Dixon, Rebecca M., et al.
Publicado: (2009)

Disruption of a Plasmodium falciparum Multidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione
por: Raj, Dipak Kumar, et al.
Publicado: (2009)

Glutamine 57 at the Complementary Binding Site Face Is a Key Determinant of Morantel Selectivity for α7 Nicotinic Receptors
por: Bartos, Mariana, et al.
Publicado: (2009)

Three-dimensional Structure of Ca(V)3.1: COMPARISON WITH THE CARDIAC L-TYPE VOLTAGE-GATED CALCIUM CHANNEL MONOMER ARCHITECTURE
por: Walsh, Conor P., et al.
Publicado: (2009)

cAMP Stimulates Apical Exocytosis of the Renal Na(+)-K(+)-2Cl(−) Cotransporter NKCC2 in the Thick Ascending Limb: ROLE OF PROTEIN KINASE A
por: Caceres, Paulo S., et al.
Publicado: (2009)

Studies on the DIDS-binding Site of Monocarboxylate Transporter 1 Suggest a Homology Model of the Open Conformation and a Plausible Translocation Cycle
por: Wilson, Marieangela C., et al.
Publicado: (2009)

Ricin A Chain Insertion into Endoplasmic Reticulum Membranes Is Triggered by a Temperature Increase to 37 °C
por: Mayerhofer, Peter U., et al.
Publicado: (2009)

Regulation of the Epithelial Na(+) Channel by the Protein Kinase CK2
por: Bachhuber, Tanja, et al.
Publicado: (2008)

Functional Expression of the Na-K-2Cl Cotransporter NKCC2 in Mammalian Cells Fails to Confirm the Dominant-negative Effect of the AF Splice Variant
por: Hannemann, Anke, et al.
Publicado: (2009)

Energy-dependent Immunity Protein Release during tol-dependent Nuclease Colicin Translocation
por: Vankemmelbeke, Mireille, et al.
Publicado: (2009)

Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes
por: Fazakerley, Daniel J., et al.
Publicado: (2010)

Structure and Function of Colicin S4, a Colicin with a Duplicated Receptor-binding Domain
por: Arnold, Thomas, et al.
Publicado: (2009)

D-AKAP2 Interacts with Rab4 and Rab11 through Its RGS Domains and Regulates Transferrin Receptor Recycling
por: Eggers, Christopher T., et al.
Publicado: (2009)

Functional Characterization of Intracellular Dictyostelium discoideum P2X Receptors
por: Ludlow, Melanie J., et al.
Publicado: (2009)

The Missing Link in Coronavirus Assembly: RETENTION OF THE AVIAN CORONAVIRUS INFECTIOUS BRONCHITIS VIRUS ENVELOPE PROTEIN IN THE PRE-GOLGI COMPARTMENTS AND PHYSICAL INTERACTION BETWEEN THE ENVELOPE AND MEMBRANE PROTEINS
por: Lim, K.P., et al.
Publicado: (2001)

Coronavirus Replication Complex Formation Utilizes Components of Cellular Autophagy
por: Prentice, Erik, et al.
Publicado: (2004)

A Novel Sorting Signal for Intracellular Localization Is Present in the S Protein of a Porcine Coronavirus but Absent from Severe Acute Respiratory Syndrome-associated Coronavirus
por: Schwegmann-Wessels, Christel, et al.
Publicado: (2004)

Aldosterone Upregulates Transient Receptor Potential Melastatin 7 (TRPM7)
por: Valinsky, William C., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ilppva0gbmqk0ng9ve82arakhp