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A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation

Methylation of histone 3 lysine 4 (H3K4) by yeast Set1-COMPASS requires prior monoubiquitination of histone H2B. To define whether other residues within the histones are also required for H3K4 methylation, we systematically generated a complete library of the alanine substitutions of all of the resi...

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Detalles Bibliográficos
Autores principales: Nakanishi, Shima, Sanderson, Brian W, Delventhal, Kym M, Bradford, William D, Staehling-Hampton, Karen, Shilatifard, Ali
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562305/
https://www.ncbi.nlm.nih.gov/pubmed/18622391
http://dx.doi.org/10.1038/nsmb.1454