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A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation
Methylation of histone 3 lysine 4 (H3K4) by yeast Set1-COMPASS requires prior monoubiquitination of histone H2B. To define whether other residues within the histones are also required for H3K4 methylation, we systematically generated a complete library of the alanine substitutions of all of the resi...
Autores principales: | Nakanishi, Shima, Sanderson, Brian W, Delventhal, Kym M, Bradford, William D, Staehling-Hampton, Karen, Shilatifard, Ali |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562305/ https://www.ncbi.nlm.nih.gov/pubmed/18622391 http://dx.doi.org/10.1038/nsmb.1454 |
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