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Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats

BACKGROUND: Periventricular leukomalacia (PVL) is a frequent complication of preterm delivery. Proinflammatory cytokines, such as interferon-γ (IFN-γ) and tumor necrosis factor α (TNF-α) released from astrocytes and microglia activated by infection or ischemia have previously been shown to impair su...

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Detalles Bibliográficos
Autores principales: Mann, Stefan A, Versmold, Beatrix, Marx, Romy, Stahlhofen, Sabine, Dietzel, Irmgard D, Heumann, Rolf, Berger, Richard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562366/
https://www.ncbi.nlm.nih.gov/pubmed/18808689
http://dx.doi.org/10.1186/1742-2094-5-39