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Somatic mutation analysis of MYH11 in breast and prostate cancer

BACKGROUND: MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia. We have previously shown that MYH11 mutations occ...

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Detalles Bibliográficos
Autores principales: Alhopuro, Pia, Karhu, Auli, Winqvist, Robert, Waltering, Kati, Visakorpi, Tapio, Aaltonen, Lauri A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562392/
https://www.ncbi.nlm.nih.gov/pubmed/18796164
http://dx.doi.org/10.1186/1471-2407-8-263