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Effects of Aneuploidy on Genome Structure, Expression, and Interphase Organization in Arabidopsis thaliana
Aneuploidy refers to losses and/or gains of individual chromosomes from the normal chromosome set. The resulting gene dosage imbalance has a noticeable affect on the phenotype, as illustrated by aneuploid syndromes, including Down syndrome in humans, and by human solid tumor cells, which are highly...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562519/ https://www.ncbi.nlm.nih.gov/pubmed/18927630 http://dx.doi.org/10.1371/journal.pgen.1000226 |